Category: Postdoc Job

Van Andel Institute: Postdoctoral Fellow, Cancer Epigenetics Training Program

Location: Grand Rapids, Michigan
Application Deadline: N/A

Looking for world-class postdoctoral training in cancer epigenetics?

Van Andel Institute is an internationally recognized center of excellence for basic and translational epigenetics research. The Institute’s Cancer Epigenetics Training (CET) program prepares postdoctoral fellows to become independent research leaders in the field of cancer epigenetics. The program offers cutting-edge, interdisciplinary research training in structural and functional aspects of epigenetics, complemented by state-of-the-art Core Technologies and Services, unique professional development activities, and integration with established translational research programs and partnerships led by VAI investigators. Fellows will emerge from the program with comprehensive training in cancer epigenetics and a professional foundation from which to launch their independent biomedical research careers. You can learn more about the program and apply, visit bit.ly/VAICETP FLYER (PDF)

Who is eligible to apply for the Cancer Epigenetics Training program?

Applicants must be near completion of a Ph.D., M.D. or other appropriate terminal degree in a scientific discipline that provides broad training in molecular biology, genetics, and/or biochemistry. Applicants must be U.S citizens or permanent residents. Individuals who identify as underrepresented minorities are strongly encouraged to apply.

Questions are welcome! Please contact Dr. Erica Gobrogge, a member of the Cancer Epigenetics Training Program leadership team and program director of VAI’s Office of Postdoctoral Affairs, at opa@vai.org.

About postdoctoral training at VAI

VAI labs conduct world-class biomedical research in cancer epigenetics, neurodegeneration, metabolism, cell biology and structural biology — all supported by outstanding Core Technologies and Services. Postdocs are a crucial part of VAI, so they receive highly competitive salaries, which start at $70,000 per year. VAI also offers postdocs comprehensive benefits, including low-cost health insurance for self and family, paid parental leave, and much more.

About Van Andel Institute Established in Grand Rapids, Michigan, in 1996 by the Van Andel family, VAI is now home to nearly 500 scientists, educators and support staff, who work with national and international collaborators to foster discovery. The Institute’s scientists study the origins of cancer, Parkinson’s and other diseases and translate their findings into breakthrough prevention and treatment strategies. Our educators develop inquiry-based approaches for K–12 education to help students and teachers prepare the next generation of problem-solvers, while our Graduate School offers a rigorous, research-intensive Ph.D. program in molecular and cellular biology.

About Grand Rapids, Michigan Van Andel Institute is in downtown Grand Rapids, Michigan in the center of the Medical Mile.  A remarkable combination of a cosmopolitan atmosphere and small-town warmth, Grand Rapids is known for its philanthropic and sustainability-driven community. It’s fun affordable and family-friendly. Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you\’d expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theatres, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walkable neighborhoods and natural areas. The downtown area is often referred to as safe and clean with an eclectic mix of walkable neighborhoods and natural areas.  

The Cancer Epigenetics Training program is supported by a National Cancer Institute T32 training grant (no. T32CA251066). The content is solely the responsibility of VAI and does not necessarily represent the official views of the National Institutes of Health.

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Van Andel Institute: Postdoc Preview

Location: Grand Rapids, Michigan
Application Deadline Date: 2/25/24

VAI Postdoc Preview provides selected applicants the opportunity to visit Van Andel Institute to learn about our postdoctoral training opportunities, meet one-on-one with our internationally recognized faculty and explore our extensive scientific resources, including our state-of-the-art Core Technologies and Services. There is no cost to attend. VAI provides transportation, lodging and meals for all selected applicants. We also are pleased to offer family care grants for those caring for children or other family members. VAI is now accepting applications for the Spring Postdoc Preview event on April 18-20, 2024. Applications are due by Feb. 25, 2024. More information and the application link are available at vai.org/postdoc-preview FLYER (PDF)

Applicants must be current graduate students at U.S. institutions who anticipate beginning a postdoctoral fellowship within the next year. Individuals who identify as members of underrepresented groups are strongly encouraged to apply. Preference will be given to applicants who are eligible for VAI’s NCI T32-funded Cancer Epigenetics Training Program and VAI’s Inspire Fellowship. Prior to starting the online application, please compile a list of VAI faculty members whose research interests you, along with your curriculum vitae.

About postdoctoral training at VAI VAI labs conduct world-class biomedical research in cancer epigenetics, neurodegeneration, metabolism, cell biology and structural biology — all supported by outstanding Core Technologies and Services. Postdocs are a crucial part of VAI, so they receive highly competitive salaries, which start at $70,000 per year. VAI also offers postdocs comprehensive benefits, including low-cost health insurance for self and family, paid parental leave, and much more. We offer numerous fully funded postdoctoral positions across our areas of focus. Learn more about postdoctoral training opportunities at VAI here. In addition, we have two internal fellowship programs: a National Cancer Institute T32-funded Cancer Epigenetics Training (CET) program, and the Inspire Fellowship program for postdocs who identify as underrepresented minorities. Please note that attending Postdoc Preview does not guarantee you a fellowship or a postdoc position at VAI; we encourage you to also apply to one or more of our open postdoc positions and fellowship opportunities (see FAQ tab on the VAI Postdoc Preview webpage for more information).

Questions? Please contact Dr. Erica Gobrogge, program director of VAI’s Office of Postdoctoral Affairs, at opa@vai.org.

About Van Andel Institute Established in Grand Rapids, Michigan, in 1996 by the Van Andel family, VAI is now home to nearly 500 scientists, educators and support staff, who work with national and international collaborators to foster discovery. The Institute’s scientists study the origins of cancer, Parkinson’s and other diseases and translate their findings into breakthrough prevention and treatment strategies. Our educators develop inquiry-based approaches for K–12 education to help students and teachers prepare the next generation of problem-solvers, while our Graduate School offers a rigorous, research-intensive Ph.D. program in molecular and cellular biology.

About Grand Rapids, MI  Van Andel Institute is in downtown Grand Rapids, Michigan in the center of the Medical Mile.  A remarkable combination of a cosmopolitan atmosphere and small-town warmth, Grand Rapids is known for its philanthropic and sustainability-driven community. It’s fun affordable and family-friendly. Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you\’d expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theatres, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walkable neighborhoods and natural areas. The downtown area is often referred to as safe and clean with an eclectic mix of walkable neighborhoods and natural areas.  

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Center for Childhood Cancer Research (CCCR): 2024 Research Recruitment Summit for Postdoctoral Scholars in Oncology

The Children’s Hospital of Philadelphia (CHOP) /University of Pennsylvania (Penn) Center for Childhood Cancer Research (CCCR) will host the 2024 Research Recruitment Summit for Postdoctoral Scholars in Oncology in Philadelphia, PA on April 29-30, 2024.

Candidates must register AND apply to be considered for program, which includes travel funds for eligible participants:

Register
Apply

The goal of this event is to bring talented late-stage graduate students and junior postdoctoral fellows onsite to (1) meet with faculty who are recruiting postdocs to work in cutting-edge research labs and learn more at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn) and to (2) engage with expert faculty on both campuses that are experts in disciplines related to cancer biology. 

The Children’s Center for Cancer Research (CCCR) is a collaboration of nationally recognized faculty from both CHOP and Penn. The center is focused on clinical and translational science with a particular emphasis on the development of immunotherapies, treatments for brain tumors, Neuroblastoma (NBL), and the Comprehensive Vascular Anomalies Program (CVAP).

Eligibility

Late-stage graduate students (within one year of completing their graduate programs) and junior postdoctoral fellows (within one to two years of receiving their doctoral degree) are eligible to apply. Candidates within the United States, including those in the Philadelphia area and region, are invited to apply. Selected candidates who live more than 50 miles from the city of Philadelphia will be eligible for coverage of travel costs.

Candidates from diverse backgrounds are strongly encouraged to apply.

Application Process

You must register (https://careers.chop.edu/us/en/event/6564fdb2bc0b5f5b49ce42db/Postdoctoral-Scholars-in-Pediatric-Oncology-Summit-April-29th-30th-2024) AND complete the application (https://redcap.chop.edu/surveys/?s=EY3Y9Y8YELNNXYA9) by February 14, 2024, to be considered. Selected applicants will receive notice of acceptance no later than March 2024.

Postdoc Salaries

CHOP and Penn offer competitive minimum salaries for postdoctoral fellows.

Years of Prior Postdoc Experience

0 = $65,000

1 = $65,500

2 = $66,000

3 = $66,500

4 = $67,000

Questions?

Please contact asiorg@chop.edu with any questions.

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Winship Cancer Institute of Emory University: Postdoc Recruitment Event

Winship Cancer Institute of Emory University invites doctoral candidates from broadly diverse backgrounds who are interested in cancer research to apply to participate in this special recruitment March 21-23, 2024 event.

Application Deadline: December 15, 2023

FLYER

CLICK HERE for more information and to apply

Questions? Contact winshipedutraining@emory.edu

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Temple University and Fox Chase Cancer Center: Postdoctoral position

A post-doctoral position is available in the Borriello laboratory, located in the Department of Cancer and Cellular Biology in the Lewis Katz School of Medicine, Philadelphia (US).

Our lab focuses on understanding the mechanisms of dormancy and metastatic recurrence, with a particular emphasis on the role of the tumor microenvironment. We use a multi-disciplinary approach to study the biology of metastasis, integrating cell signaling, biochemistry, molecular biology, multiplex tissue imaging, several mouse models, and intravital imaging of tumor cells in live animals. Additional information on our research program can be found on our website: www.borriellolab.com.

Description
The Borriello Lab is seeking highly motivated and enthusiastic postdoctoral fellow to join our research team. We collaborate with investigators from both within the Lewis Katz School of Medicine and Fox Chase Cancer Center.

The successful candidate will have the unique opportunity to work in a dynamic and stimulating academic environment, at a top-notch institution in the US. The Borriello Lab is committed to building an inclusive environment that supports professional development and scientific discoveries.

Qualifications
• The candidate should either already possess, or be in the final stages of obtaining a PhD in cancer biology, cell and molecular biology, biomedical sciences, or a related field. A strong background in tumor signaling, tumor microenvironment, cancer progression and metastasis is highly valued.
• The ideal candidate should have experience in basic molecular and cellular biology methods. Experience with mouse modeling and handling is highly desirable.
• The candidate is expected to be highly motivated, creative, well organized, and capable of contributing productively in a team environment.
• The candidate is also expected to analyze and interpret results, review and present data for publications and presentations, write scientific papers, and engage in departmental seminars and activities.
• Excellent communication skills in written and oral English are essential.

If you are interested in joining our research program, please submit a cover letter describing your motivation to apply, copy of current curriculum vitae, and a list of three references directly to:
Lucia Borriello, PhD
Assistant Professor
Department of Cancer and Cellular Biology, Lewis Katz School of Medicine Fox Chase Cancer Center

FLYER

Application Deadline Date: March 2024

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University of Kentucky Markey Cancer Center: Postdoctoral Scholar

The Markey Cancer Center is currently seeking a Post-doctoral Scholar who will be trained under Dr. Pamela Hull. This position offers an intensive mentored training experience in community-engaged research, implementation science, quality improvement, and implementation of evidence-based guidelines for cancer prevention and control (e.g., HPV vaccine, cancer screenings, social needs and patient navigation during cancer treatment). The training experience includes working on all aspects of community engagement efforts and research projects, disseminating research findings, and developing a research agenda to prepare for transitioning to an independent community-engaged researcher and implementation scientist in a faculty position. Job responsibilities include but are not limited to the following: assist with data collection and analysis, assist with development of intervention content, prepare measurement tools and study protocols, collaborate with community partners, plan and implement dissemination activities, prepare scientific manuscripts as lead author and co-author, present research at conferences, and submit at least one funding application.

To apply you will need to upload the following documents: CV, Cover Letter, and as Specific Request I, a writing sample.

Skills / Knowledge / Abilities: Experience or demonstrated interest in implementation science, cancer prevention/control, health disparities, health behavior interventions, and evidence-based interventions/practices.

Preferred Education/Experience: Demonstrated evidence of a research agenda focused on cancer prevention and control (e.g., HPV vaccination, cancer screening, social needs and patient navigation during cancer treatment) and demonstrated interest in community-engaged research and implementation science. Experience working with populations that experience health disparities, such as racial/ethnic minorities, rural, Appalachian, and/or low-income populations.

Application Deadline Date: 11/29/2023

For more information, contact: erinjoakley@uky.edu

CLICK HERE for more information and to apply

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University of Minnesota Masonic Cancer Center: Postdoctoral Fellows

Job location: Minneapolis, Minnesota
Application Deadline Date: OPEN

Postdoctoral positions in the Lange Lab: Seeking individuals driven to become future scientists and leaders in the field of hormones and cancer within academic basic and translational research, clinical, educational, regulatory, or other science-related careers.

My research team is focused on the role of steroid hormone receptors (SRs) in hormone-driven cancers. Estrogen receptor (ER) and progesterone receptors (PRs) are context-dependent transcription factors that are essential for development of the breast and reproductive tract. Altered sex hormone levels contribute to cancer risk in these tissues and drive metabolic and cell fate transitions associated with rapid tumor progression. The presence of abnormally activated ERs and imbalanced/activated PR isoforms in SR+ tumors can dramatically influence response to endocrine or other therapies. Our overarching research goal is to better understand how SR+ breast cancers and other hormone-influenced cancers of reproductive tissues escape endocrine (i.e. SR-blocking) or other molecular targeted therapies that primarily target proliferating cells. Strategies aimed at targeting metabolically active, but weakly proliferative or non-proliferative (G0) cancer stem or heterogeneous stem-like cell sub-populations as well as highly migratory dormant or quiescent cells (i.e. living as disseminated “active” G0 cells in the circulation or within distant “cancerized” tissue niches) would provide a powerful complement to existing therapeutic strategies. Novel signaling pathway biomarkers may inform new combination therapies.

Signal transduction is an essential role of SRs. Indeed, all SRs can rapidly activate cytoplasmic protein kinases and act as “growth factor sensors”. In this role, SRs are heavily phosphorylated by mitogenic protein kinases (MAPKs, AKT, CDKs) that are frequently elevated and activated in breast and reproductive tract cancers. Phosphorylation of SRs alters their binding partners and promoter selection and influences cancer cell fate/plasticity by regulating genes that specify proliferative, pro-survival, metabolic, and cancer stem cell programs via expression of both autocrine and paracrine factors. Similarly (i.e. via rapid signaling and phosphorylation events), the glucocorticoid receptor (GR) acts as a sensor for both host (i.e. hormonal) and cellular stress, in the form of local cytokines and/or hypoxic conditions within the tumor microenvironment. Identifying the required kinase and co-activator partners of phospho-SRs will enable the targeting of multiple signaling molecules in addition to SRs, which is predicted to halt cancer metastasis, prevent recurrence, and increase patient survival.

My lab has extensive experience developing and using human cancer cell lines and primary cells, genetically modified mouse models, and human tumor specimens. We have routinely developed new reagents and employed classical biochemistry and molecular biology techniques to study SR action and novel mechanisms of gene regulation that impact breast tumor development and progression, cancer stem cell biology, and endocrine therapy resistance. More recently, we have included significant focus on the development of early SR+ fallopian tube lesions that give rise to high grade serous ovarian cancer. We typically complement in vitro studies focused on the mechanisms of signaling inputs to SR-dependent regulation of transcription with the use of genetically modified mice or human patient derived xenograft (PDX) models maintained in mice.

Ongoing projects encompass the following research themes and their molecular mechanisms:

• ER? and PR isoform signaling cross talk in luminal breast cancer progression
• Ligand-independent actions of p-SRs and p-SR-containing complexes in breast cancer
• Cellular “stress” sensing by phospho-GR in triple negative breast cancer progression
• Novel HIF/GR-induced signaling pathways mediated by Breast Tumor Kinase/PTK6
• Fallopian tube transformation and early SR+ serous ovarian cancer progression
• Cell fate plasticity (cell cycle exit/entry into G0) and breast cancer stem cell biology
• Mechanisms of and biological role of cancer cell dormancy/quiescence and senescence
• SR and signaling pathway regulation of breast cancer stem cell populations and biology
• Inflammatory and tumor microenvironmental inputs to altered SR signaling in SR+ tumors
• Breast cancer metastatic cell dissemination as circulating tumor cell/stem cell clusters

SEND CV and list of 2-3 references to Dr. Carol A. Lange at lange047@umn.edu

PDF version

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